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  • Nucleic Acid Delivery by Solid Lipid Nanoparticles Containing . . .
    SLN1, SLN2 and SLN4 showed similar particle size ranging from 185 to 211 nm, PDI values lower than 0 4 and superficial charge higher than +40 mV However, SLN3, prepared without the cationic lipid DOTAP, presented a particle size higher than 400 nm, PDI higher than 0 5 and negative surface charge of −28 mV
  • Size and surface charge characterization of nanoparticles . . .
    From a single measurement lasting less than minutes, we can accurately determine both the particle size and zeta potential for individual particles, ensembles of particles, or even particle
  • Particle size distribution of solid lipid nanoparticles (1 . . .
    The Cs-SLN have mean particle size of 373 9 ±1 41 nm, polydispersity index (PDI) of 0 342±0 02 and the entrapment efficiency for AmB and PM was found to be 95 20±3 19 % and 89 45± 6 86 %
  • Nucleic Acid Delivery by Solid Lipid Nanoparticles Containing . . .
    SLN1, SLN2 and SLN4 showed similar particle size ranging from 185 to 211 nm, PDI values lower than 0 4 and superficial charge higher than +40 mV However, SLN3, prepared without the cationic lipid DOTAP, presented a particle size higher than 400 nm, PDI higher than 0 5 and negative surface charge of −28 mV
  • Major difference in particle size, minor difference in . . .
    SLN were synthesized via the hot high-pressure homogenization (HPH) method, budesonide (BUD) was used as the model drug, and BUD-SLN1-BUD-SLN4 with increasing particle size was obtained, i e 120, 240, 360, and 480 nm The prepared SLN has good encapsulation efficiency, drug loading capacity, and stability
  • Optimization of the Conditions of Solid Lipid Nanoparticles . . .
    The average particle size just after the synthesis of unmodified SLN1 ranged from 255 50 ± 7 88 to 383 60 ± 2 60 nm, and after 5 days of storage in both cases, it was larger than immediately after the synthesis; this could indicate a gradually developing particle agglomeration
  • A Deep Dive into Lipid Nanoparticle Size Distribution
    A low PDI signifies a narrow size distribution, crucial for ensuring consistent behaviour and performance In contrast, a higher PDI (> 0 3) indicates a broad size distribution with a higher degree of variability in the particle size





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