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  • Gleason 3+4 Prostate Cancer? Think Twice Before Active Surveillance
    The rate of newly diagnosed patients with Gleason 3+3 (Grade Group 1) prostate cancer (PCa) who choose go on Active Surveillance (AS) instead of immediate treatment has increased significantly in the last decade There’s considerable expert opinion that Gleason 3+3 PCa does not behave like cancer and may never become life threatening
  • Point: Should Active Surveillance Be Used for Gleason 3+4 Prostate Cancer?
    The recent National Comprehensive Cancer Network (NCCN) guidelines list active surveillance as an initial therapy option for men with favorable intermediate-risk disease, which they define as clinical stage T2b-T2c, Gleason score 3+4, or prostate-specific antigen (PSA) levels at 10–20 ng mL, as well as less than 50% of positive biopsy cores [2]
  • Active Surveillance for Prostate Cancer - Johns Hopkins Medicine
    Patients with low-grade, slow-growing tumors confined to the prostate gland may consider active surveillance This involves monitoring prostate cancer in its localized stage until your doctor feels that further treatment is needed to halt the disease at a curable stage
  • Active surveillance for prostate cancer - Mayo Clinic
    Active surveillance for prostate cancer may be appropriate for you if: Your cancer is small If your cancer is found early, while it's still small and limited to one area of your prostate, active surveillance may be a reasonable choice Your Gleason score is low
  • Questions about Active Surveillance as a treatment option
    But with 3+4, you have the whole range of options available, and have to decide how to trade off the risk of the cancer progressing under active surveillance against the other long-term health risks from hormone therapy, surgery, and or radiation That uncertainty (there's no way to know you've made the "right" choice) must generate a lot of
  • Observation or Active Surveillance for Prostate Cancer
    Some men with slow-growing prostate cancers (especially men who are older or have other serious health problems) might never need treatment Instead, their doctors may recommend active surveillance or observation (sometimes called watchful waiting) What are active surveillance and observation?
  • Active surveillance should be considered for select men with Grade . . .
    While Active Surveillance (AS) is the recommended option for men with Grade Group 1 (Gleason Score 3 + 3 = 6) prostate cancer without other intermediate-risk features, men with Grade Group 2 (Gleason Score 3 + 4 = 7) are typically recommended active treatment
  • Active Surveillance of Prostate Cancer - PMC
    Patients who harbor low-volume 3+3 tumors or 3+4 tumors with only a small percentage of grade 4 are eligible for active surveillance The use of active surveillance in the United States has increased in recent years, with over 40% of low-risk tumors managed in this manner, and even higher rates for men over 75 years of age [ 1 ]
  • Using active surveillance for Gleason 7 (3+4) prostate cancer: A . . .
    The interest in broadening the application of active surveillance (AS) has been increasing, encompassing patients who may not strictly adhere to the conventional criteria for low-risk prostate cancer (PCa), particularly those diagnosed with small-volume Gleason grade group 2 disease
  • Active Surveillance for Prostate Cancer - UCSF Health
    Active surveillance may also be an option for some patients with slightly higher risk cancers (such as those with a low-volume Gleason score of 3+4), especially if imaging or genomic testing results are reassuring





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