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  • CBD and Sleep: What Science Says About REM Deep Sleep - CBD Oracle
    One study on people with obstructive sleep apnea noted increased N3 sleep and decreased REM sleep in people who use cannabis (including both THC and CBD dominant products) For CBD specifically, results from studies of humans are inconsistent, with some finding no difference whatsoever
  • Effects of Cannabinoids on Sleep and their Therapeutic . . . - Springer
    CBD use has been shown to increase total sleep percentage with mid to high doses in rat models There is a dose-dependent effect on REM sleep latency—with higher doses causing an increase in latency while mid-range doses yield a decrease Another study found that CBD had a positive effect on anxiety-related REM sleep suppression but no
  • A double-blind, randomized, placebo-controlled study of the safety and . . .
    Findings suggest 20 mg of CBN taken nightly may be helpful for improving overall sleep disturbance, including the number of times one wakes up throughout the night, without impacting daytime fatigue The present study serves as the first placebo-controlled study of CBN for sleep
  • A Cannabidiol Terpene Formulation That Increases Restorative Sleep in . . .
    crossover study to investigate how an oral formulation of cannabidiol (CBD) and terpenes influences sleep physiology in participants who suffer from insomnia In contrast to many prescription sleep medicines and over-the-counter sleep aids, the CBD-terpene formulation increased SWS and REM
  • 0557 Effects of a Cannabidiol Terpene Formulation on Sleep in . . .
    Cannabidiol (CBD) is increasingly used as a health supplement, though few clinical studies have demonstrated benefits The primary objective of this study was to evaluate the effects of an oral CBD-terpene formulation on sleep physiology in individuals with insomnia
  • Cannabis, Cannabinoids, and Sleep: a Review of the Literature
    Recent Findings Preliminary research into cannabis and in-somnia suggests that cannabidiol (CBD) may have therapeutic potential for the treatment of insomnia Delta-9 tetrahydrocan-nabinol (THC) may decrease sleep latency but could impair sleep quality long-term
  • Cannabinoids and Sleep: Exploring Biological Mechanisms and . . . - MDPI
    Clinical studies suggest that CBD modulates endocannabinoid signaling through several receptor sites, offering a multifaceted approach to sleep regulation Similarly, palmitoylethanolamide (PEA), in addition to interacting with the endocannabinoid system, acts as an agonist on peroxisome proliferator-activated receptors (PPARs)
  • Objective Evidence That Supports CBD for Insomnia - Sleep Review
    A randomized controlled trial found a CBD-terpene formulation increased restorative sleep in insomnia patients, providing novel insights into the effects of cannabidiol on sleep physiology Interview by Alyx Arnett
  • The Science of CBD and Its Impact on Sleep Cycles
    What is CBD and How Does It Work? The Role of Sleep Cycles in Health Understanding Sleep Stages REM Sleep: The Dream Stage; Non-REM Sleep: The Restorative Phase; How CBD Affects Sleep Cycles; Scientific Studies on CBD and Sleep Clinical Trials and Findings; Mechanisms Behind CBD’s Sleep Benefits; Potential Benefits of CBD for Sleep Disorders
  • How THC and CBD Impact Sleep Cycles: What the Science Says
    Tetrahydrocannabinol (THC), the psychoactive component of cannabis, has been shown to have sedative properties Research indicates that THC can help individuals fall asleep faster and extend deep sleep stages However, it also reduces REM sleep—the stage associated with dreaming and cognitive processing





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