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  • Late-onset Ocular Toxicity Presenting as Uveitis Caused by Crizotinib
    A 64-year-old female complained of blurred vision in the right eye 1 week after daily crizotinib (500 mg) administration had been started for intrapulmonary metastases after lung cancer surgery The patient suffered from ALK-positive NSCLC and had a history of breast cancer with complete remission
  • Crizotinib: Uses, Dosage, Side Effects, Warnings - Drugs. com
    Vision problems are common with crizotinib These usually happen within 1 week of starting treatment and can be severe and may cause partial or complete loss of vision in one or both eyes Tell your healthcare provider right away if you have any new vision problems, loss of vision, or any vision change, including:
  • Ophthalmological assessment of crizotinib in advanced non-small-cell . . .
    In preliminary and updated analyses of a single-arm trial of crizotinib in patients with ALK-positive advanced NSCLC, predominantly grade 1 or 2 visual disturbances were among the most common adverse events (AEs), including, but not limited to, light trails, flashes or brief image persistence
  • Ophthalmological assessment of crizotinib in advanced non-small-cell . . .
    During crizotinib treatment, ophthalmologic changes from baseline did not appear to be associated with patient-reported ocular TEAEs Abnormal ophthalmologic findings occurred in the context of preexisting conditions for a number of patients
  • DRUG NAME: Crizotinib - BC Cancer
    risks of resuming crizotinib following severe vision loss are not known Patients experiencing vision disorders should be cautious when driving or operating machinery
  • Crizotinib: MedlinePlus Drug Information
    you should know that crizotinib may cause vision problems, including vision loss Your doctor may tell you to have an eye exam before starting your treatment and during your treatment with crizotinib
  • Understanding Visual Disturbances: Side Effects of Targeted Therapy . . .
    Among the most commonly reported side effects, especially for patients on crizotinib, are visual disturbances Understanding these side effects and how to manage them can help patients navigate their treatment journey more comfortably and stay on their TKI as long as possible
  • Xalkori (crizotinib) : Uses, Side Effects, Dosage Reviews - GoodRx
    Xalkori (crizotinib) can cause vision changes such as blurred vision and not seeing as well In rare cases, people have experienced near total vision loss If you’re an adult, you should see an ophthalmologist before you start crizotinib and once a month while you’re still taking it
  • Neuro-ophthalmic side effects of molecularly targeted cancer drugs
    Molecularly targeted therapy is a concept in which specific cellular molecules (overexpressed, mutationally activated, or selectively expressed proteins) are manipulated in an advantageous manner to decrease the transformation, proliferation, and or survival of cancer cells
  • Crizotinib - Chemocare
    CRIZOTINIB (kriz OH ti nib) treats some types of cancer It works by blocking a protein that causes cancer cells to grow and multiply This helps to slow or stop the spread of cancer cells This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions





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