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  • The Mouse Papillomavirus Infection Model - PMC - PubMed Central (PMC)
    Specifically, we discuss viral pathogenesis in cutaneous and mucosal tissues as well as in different mouse strains, immune responses to the virus, and local host-restricted factors that may be involved in MmuPV1 infections and associated disease progression
  • Monitoring mouse papillomavirus-associated cancer development using . . .
    A substantial percentage of the population remains at risk for cervical cancer due to pre-existing human papillomavirus (HPV) infections, despite prophylactic vaccines Early diagnosis and treatment are crucial for better disease outcomes
  • mSphere of Influence: MmuPV1—a dual tropic papillomavirus, red herring . . .
    In this mSphere of Influence article, they reflect on how the article “Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancer” impacted them, informing their research strategies, and what it means for the mouse papillomavirus model in situ in vivo in vitro
  • Monitoring mouse papillomavirus-associated cancer development . . . - mBio
    Recently, we established a mouse papillomavirus (MmuPV1) model that is relevant to HPV genital pathogenesis In the current study, we validated the use of Papanicolaou (Pap) smears, a valuable early diagnostic tool for detecting HPV cervical cancer, to monitor disease progression in the MmuPV1 mouse model
  • Immune Responses in Oral Papillomavirus Clearance in the MmuPV1 Mouse . . .
    In the current study, we use genetically modified mice to target CCR2 and Stat1 pathways, with the aim of investigating the role of both innate and adaptive immune responses in clearing oral papillomavirus, using our established papillomavirus (MmuPV1) infection model
  • Immunologic Control of Mus musculus Papillomavirus Type 1
    While most patients clear human papillomavirus (HPV) infection, some develop persistent papillomas, especially if immunocompromised Likewise, we find a fraction of outbred SKH-1 mice challenged with Mus musculus papillomavirus type 1 (MusPV1 MmuPV1) develop persistent papillomas, whereas most SKH-1 mice, as seen for the inbred C57BL 6 and BALB
  • Development of an in vivo infection model to study Mouse papillomavirus . . .
    Preclinical model systems to study multiple features of the papillomavirus life cycle are extremely valuable tools to aid our understanding of Human Papillomavirus (HPV) biology, disease progression and treatments Mouse papillomavirus (MmuPV1) is
  • Novel Laboratory Mouse Papillomavirus (MusPV) Infection
    We report here identification of a cutaneous laboratory mouse PV (MusPV) and the lesions associated with this infection All mice were housed at the Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Kharghar, Navi Mumbai, India
  • The Mouse Papillomavirus Infection Model - PubMed
    Specifically, we discuss viral pathogenesis in cutaneous and mucosal tissues as well as in different mouse strains, immune responses to the virus, and local host-restricted factors that may be involved in MmuPV1 infections and associated disease progression
  • Mus musculus Papillomavirus 1: a New Frontier in Animal Models of . . .
    In this Gem, we discuss the discovery of a murine papillomavirus, Mus musculus papillomavirus 1 (MmuPV1), and how its experimental use represents a major advancement in models of papillomavirus-induced pathogenesis carcinogenesis, and their transmission





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