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  • Guideline: optimal serum and red blood cell folate concentrations in . . .
    What is the threshold concentration of blood folate associated with the lowest probability risk (depending on the statistical method) of having a pregnancy affected by neural tube defects? Do blood folate concentrations respond to interventions to improve folate status in women?
  • GUIDELINE - World Health Organization
    determinants of folate status (serum, plasma or red blood cell folate) in women of reproductive age? 2 What is the threshold concentration of blood folate associated with the lowest probability risk
  • Optimal Serum and Red Blood Cell Folate Concentrations in Women of . . .
    At the population level, RBC folate concentrations should be >400 ng mL (906 nmol L) in women of reproductive age to achieve the greatest reduction of NTDs (strong recommendation, low-quality evidence †)
  • HHS Public Access - CDC Stacks
    Background: For women of reproductive age, a population-level red blood cell (RBC) folate concentration below the threshold 906 nmol L or 400 ng mL indicates folate insufficiency and suboptimal neural tube defect (NTD) prevention
  • Red Blood Cell Folate Testing - CAP
    Folate levels can be measured in serum and in erythrocytes (RBC folate) Approximately 95% of folate is located within erythrocytes, so historically, RBC folate has been thought to better assess longer-term folate storage, whereas serum folate levels may reflect more recent dietary folate intake
  • BIOMARKER SURVEILLANCE IN WOMEN OF REPRODUCTIVE AGE FOR ANEMIA AND . . .
    A total of 79 3% of women had RBC folate concentrations below the threshold for optimal NTD prevention Among WRA with sufficient vitamin B12 status (≥221 pmol L), the estimated sf-IT was consistent with previous Bayesian analyses
  • Estimating the Serum Folate Concentration Associated With the Red Blood . . .
    To estimate the serum folate insufficiency threshold (sf-IT) corresponding to the red blood cell (RBC) folate insufficiency threshold for optimal neural tube defect (NTD) prevention Participants were 977 women of reproductive age (WRA; 15–40y; not pregnant or lactating) from a population-based biomarker survey in Southern India
  • Optimal Serum and Red Blood Cell Folate Concentrations in Women of . . .
    1 At the population level, RBC folate concentrations should be >400 ng mL (906 nmol L) in women of reproductive age to achieve the greatest reduction of NTDs (strong recommendation, low-quality evidence †) 2 The RBC folate threshold of >400 ng mL (906 nmol L) can be used as an indicator of folate insufficiency in


















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