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  • miR-590-5p: A double-edged sword in the oncogenesis process
    Accumulating evidence suggests the critical role of miR-590-5p in various aspects of cellular homeostasis, including cancer Furthermore, we and others have recently demonstrated that miRNA-590-5p acts as an oncogene in some cancers while it acts as a tumor-suppressor in others
  • Overview of miR-106a Regulatory Roles: from Cancer to Aging
    In a study conducted by Zhou et al , an miRNA signature consisting of five upregulated miRNAs (miR-106a, miR-18a, miR-20b, miR-486-5p, and miR-584) and one down-regulated miRNA (miR-223-3p) was identified as a potential biomarker for the diagnosis of ESCC
  • MiR-106a-5p inhibits the cell migration and invasion of renal . . .
    MicroRNA-106a-5p (MiR-106a-5p), a small non-coding RNA, has been reported to be downregulated in astrocytoma, osteosarcoma and colorectal cancer
  • MiR-106a: Promising biomarker for cancer - ScienceDirect
    Upregulated levels of four plasma miRNAs (miR-106a-3p, miR-106a-5p, miR-20b-5p, and miR-92a-2-5p) and four serum miRNAs (miR-106a-5p, miR-19b-3p, miR-20b-5p, and miR-92a-3p) were identified and validated in BC
  • MiR-106a-5p inhibits the cell migration and invasion of renal . . .
    Our in vivo studies showed that overexpressed miR-106a-5p in RCC cells inhibited the nodular metastasis in the lungs of nude mice versus negative control groups, which was in line with our in vitro experiments
  • Tumor Suppressor miRNA in Cancer Cells and the Tumor . . .
    Extensive profiling studies have shown that the regulation of mature miRNAs expression plays a causal role in cancer development and progression miRNAs have been identified to act as tumor suppressors (TS) or as oncogenes based on their modulating effect on the expression of their target genes
  • miR-590-5p inhibits tumor growth in malignant melanoma by . . .
    In the present study, miR-590-5p was identified to be upregulated in MM cells compared with human melanocytes using a reverse transcription-quantitative polymerase chain reaction to screen established oncogenic and tumor suppressor miRNAs miR-590-5p was demonstrated to inhibit the cell proliferation and tumor growth of MM cells in vitro and in





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