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  • People With Severe Diabetes Are Cured in Small Trial of New Drug
    A person’s conventional supplies for treating type 1 diabetes A single infusion of a new treatment, called zimislecel, may have cured 10 out of 12 people with the most severe form of the disease
  • Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist . . .
    Orforglipron is a small-molecule, nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist in clinical development for type 2 diabetes and weight management Additional data on the efficacy and
  • Stem Cell-Derived Islet Therapies Shown to Reduce the Need . . .
    Stem Cell-Based Treatment with Safety Switch Shows Potential for Patients with Type 1 Diabetes Findings demonstrating the early-stage success of genetically modified stem cell-derived islet (SC-islet) replacement therapies for the treatment of type 1 diabetes, leveraging a novel safety feature, were presented as a late-breaking poster
  • Adjunct-to-insulin therapy using SGLT2 inhibitors in youth . . .
    Sodium glucose co-transporter 2 inhibitors (SGLT2i) reduce the risk of chronic kidney disease (CKD) progression in type 2 diabetes, but their effects in type 1 diabetes (T1D) are not completely
  • World’s first: stem cell therapy reverses diabetes - PMC
    VX-880 is an experimental stem cell-derived therapy being tested in a phase 1 2 clinical trial for people with type 1 diabetes (T1D) who struggle with severe hypoglycemia and have impaired hypoglycemic awareness
  • Son’s diabetes diagnosis sent scientist on quest for cure
    Now, more than 30 years later, Melton and his colleagues are within sight of a new treatment for Type 1 diabetes that uses stem cells to make healthy insulin-producing cells that can be transplanted into patients Vertex Pharmaceuticals, a biomedical company headquartered in Boston, is running clinical trials on methods pioneered by Melton and
  • Stem Cell Breakthrough Offers Hope for Type 1 Diabetes Cure
    In a groundbreaking evolution of diabetes therapy, scientists have made a major leap toward a sustainable, potentially curative treatment for type 1 diabetes For decades, the primary strategy for treating this autoimmune disease has revolved around the administration of exogenous insulin





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