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  • The interplay between cytokines, inflammation, and . . .
    Pro-inflammatory cytokines, such as interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6), can stimulate the generation of ROS through the activation of various cellular pathways
  • Inflammasome activation and regulation: toward a better . . .
    In the present review, we summarize the most recent advances and remaining challenges in understanding the ordered inflammasome assembly and activation upon sensing of diverse stimuli, as well as
  • Cytokines in Inflammatory Disease - PMC
    Furthermore, it leads to the induction, production and the release of pro-inflammatory mediators, including cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-1, IL-6 and IL-10, or type 1 interferons (IFNs)
  • Inflammatory Process and Role of Cytokines in Inflammation . . .
    The activity of various leukocytes is suppressed by IL-4 and IL-10 (anti-inflammatory cytokines) that triggers the production of pro-inflammatory cytokines
  • Regulation of cytokine signaling and inflammation
    In this review, we provide examples of the relationship between cytokine signal transduction, negative-signal regulation, and inflammatory disease models Furthermore, we illustrate several approaches for treating inflammatory diseases by modulating extracellular and intracellular signaling pathways 1 Introduction
  • Regulation of autoimmune inflammation by pro-inflammatory . . .
    The modulation of disease can be achieved either by direct injection of the pro-inflammatory cytokine (TNF-α IFN-γ) or by immunization with a peptide protein that activates T cells producing predominantly Th1 type pro-inflammatory cytokines





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