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upriver    音标拼音: [,ʌpr'ɪvɚ]
a. 上游的,向水源的
n. 上流区域

上游的,向水源的上流区域


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  • Exploring the Potential of Lapatinib, Fulvestrant, and Paclitaxel . . .
    Three cell lines were selected as a therapeutic target for the glycidylated PAMAM G4 conjugates with paclitaxel, fulvestrant, and or lapatinib: A549 non-small-cell lung cancer, U-118 MG glioma cells, and comparatively non-cancerous, immortalized human keratinocytes
  • Distinct mechanisms of resistance to fulvestrant treatment dictate . . .
    To study the complexity of the mechanisms involved in the resistance to the selective estrogen receptor degrader (SERD) fulvestrant, we performed comprehensive biomarker analyses using several in vitro models that recapitulate the heterogeneity of developed resistance
  • Combination treatment with fulvestrant and various cytotoxic agents . . .
    We examined combinations of chemotherapeutic agents (doxorubicin, paclitaxel, docetaxel, vinorelbine, and 5-fluorouracil) with hormone drugs (tamoxifen, its active metabolite, 4-hydroxytamoxifen, and fulvestrant) based on the combination index (CI) in ER-positive human breast cancer cell lines
  • A Phase II Study of Fulvestrant 500 mg as Maintenance Therapy in . . .
    In our study, we showed a PFS of 16 1 months with fulvestrant 500 mg maintenance therapy However, whether fulvestrant can challenge the predominance of aromatase inhibitor in maintenance setting still needs to be verified by randomized controlled trials
  • Breast Cancer SACT Protocols - Clatterbridge Cancer Centre NHS . . .
    ALPELISIB (Piqray®) and FULVESTRANT Locally Advanced and Metastatic Breast Cancer: Atezolizumab Paclitaxel Albumin (Abraxane) TRIPLE NEGATIVE BREAST CANCER V2 0: Capecitabine Breast Cancer Protocol : Capivasertib and Fulvestrant V1 0: Carboplatin and Gemcitabine Breast Cancer: Carboplatin AUC 2 Metastatic Breast Cancer
  • Clinical benefit of fulvestrant monotherapy in the multimodal treatment . . .
    Fulvestrant is a valuable option with limited toxicity and durable response in metastatic HER2 and ER positive breast cancer after progression on anti-HER2 agents as well Therapeutic benefit even in extensive skin metastases and (irradiated) brain metastases may be expected
  • Breast Cancer - thamesvalleycanceralliance. nhs. uk
    Paclitaxel may be administered via a DEHP free line instead of the polyethylene lined giving set specified in the regimens Trastuzumab deruxtecan and trastuzumab emtansine should be administered via administration sets with polyethersulfone (PES) ≤0 22micron inline filter (but do not require polyethylene lined giving set)
  • Combination of fulvestrant and chemotherapy in ESR1 Y537S mutant breast . . .
    Methods: We performed synergy studies testing the combination of fulvestrant with chemotherapy treatments commonly used in ER+ metastatic breast cancer including 5FU (representing capecitabine), adriamycin and paclitaxel using MCF7 and T47D breast cancer cell lines engineered to express doxycycline inducible Y537S-ESR1 mutation
  • New pharmacological effect of fulvestrant to prevent oxaliplatin . . .
    Thus, our findings reveal a previously unrecognised pharmacological effect of fulvestrant to prevent oxaliplatin-induced painful peripheral neuropathy without impairing its cytotoxicity against cancer cells and may represent a novel prophylactic option for patients receiving oxaliplatin chemotherapy What's new?





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