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azole

氮杂茂

The Collaborative International Dictionary of English v.0.48 (gcide)

Azole \Az"ole\, n. [From {Azote}.] (Org. Chem.)
Any of a large class of compounds characterized by a
five-membered ring which contains an atom of nitrogen and at
least one other noncarbon atom (nitrogen, oxygen, sulphur).
The prefixes furo-, thio, and pyrro- are used to distinguish
three subclasses of azoles, which may be regarded as derived
respectively from furfuran, thiophene, and pyrrol by
replacement of the {CH} group by nitrogen; as, furo-monazole.
Names exactly analogous to those for the azines are also
used; as, oxazole, diazole, etc.
[Webster 1913 Suppl.]

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Azole - Wikipedia
One, and only one, lone pair of electrons from each heteroatom in the ring is part of the aromatic bonding in an azole Names of azoles maintain the prefix upon reduction (e g , pyrazoline, pyrazolidine)
List of Azole antifungals - Drugs. com
Azole antifungal agents can be used to treat fungal infections of the body and skin, including athlete's foot, onychomycosis (fungal nail infections), ringworm, and vaginal candidiasis
Pharmacology of azoles - UpToDate
The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole) An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here
Popular Azole Antifungals List, Drug Prices and Medication . . . - GoodRx
Compare the cost of prescription and generic Azole Antifungals medications See information about popular Azole Antifungals, including the conditions they treat and alternatives available with or without insurance
New Antifungal Agents with Azole Moieties - PMC
Most used antifungal agents are included in the class of azoles This family of compounds has shown over the decades a vast range of applications in the treatment of fungal infections and diseases, with increasing interest and use in the clinical setting
Azoles: A Complete Guide to Antifungal Agents, Their Mechanism . . .
Azoles are synthetic antifungal agents that inhibit fungal growth by targeting ergosterol synthesis, a critical component of the fungal cell membrane They are categorized into two primary groups based on their molecular structure: imidazoles and triazoles
Azole Antifungals Comparison – Indications and Coverage
Azole antifungals play a central role in the treatment and prevention of fungal infections, offering coverage against yeasts, molds, and dimorphic fungi depending on the agent
Azoles - an overview | ScienceDirect Topics
Azoles are nitrogen, sulfur, and oxygen-containing compounds with a five-membered ring system that comprises thiadiazole, oxadiazole, triazole, imidazole, isoxazole, pyrazole, and other rings
Azoles: pentagonal heterocycles with two or more heteroatoms
They are derived from furan, thiophene and pyrrole, by replacement of one or more CH groups by sp2 -hybridized nitrogens It is the variation in the number and positions of the nitrogen atoms that gives rise to the great structural diversity of this group of heterocycles
Azole antifungals - Life Worldwide - Fungal Education
Many different topical azoles are available clinically for thrush (yeast infection) but not all are included here Azole antifungals interfere with fungal biosynthesis of ergosterol, by inhibiting 14-α demethylase

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